Age Zero Exosomes™
Quite Possibly
THE WORLD’S MOST POTENT
TOPICAL EXOSOME SERUM
What Is Age Zero Exosomes™
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AGE ZERO Exosomes™ are nano-sized vesicles (30–150nm) that deliver essential molecules like lipids, RNA, growth factors, and cytokines to support cellular communication and repair.
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These exosomes play a critical role in signaling between cells, triggering natural rejuvenation processes, and helping to promote healthy-looking skin and scalp vitality.
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AGE ZERO Exosomes™ are a next-generation cosmetic innovation in skin and scalp care, offering advanced support for professionals looking to enhance their aesthetic treatment offerings.
How It Works
Delivers Regenerative Signals
Exosomes transport key biomolecules, such as growth factors and cytokines, which are known to play a role in cellular communication and help support the skin and scalp’s natural renewal processes.
Stimulates Cellular Performance
By interacting with skin and scalp receptors, these exosomes are intended to support natural cellular activity involved in collagen production and tissue renewal, helping improve the appearance of skin firmness and hair vitality.
Ethically Sourced, Scientifically Backed
Resiliélle™ exclusively uses stem cells from Wharton’s Jelly in the human umbilical cord, selected for their extraordinary regenerative potential. These cords are donated in strict compliance with FDA ethical standards, following healthy, live, full-term births. Resiliélle™ exosomes have never been tested on animals.
Next-Gen Skin & Hair Optimization
Formulated to support overall skin and scalp wellness, helping enhance the appearance of tone, texture, and elasticity, while promoting refreshed, healthier-looking skin and hair.
Disclaimer: RESILIÉLLE™ exosomes are for topical cosmetic use only.
Key Benefits
Supports Skin and Scalp Revitalization
Helps Support the Body’s Natural Healing and Recovery Processes
Supports Smoother Skin Texture and More Even Tone
Helps Improve the Appearance of Fine Lines and Wrinkles
Ethically Sourced
Safety-Focused
Made In The USA
Non-Invasive
Generally Well-Tolerated
Where Excellence Isn’t an Option
It’s the Standard
Age Zero™ Potency
Derived from Wharton's Jelly MSCs immediately after birth, when regenerative potential is at its peak, for unmatched rejuvenation power.
Low-Passage, High-Bioactivity
Produced using a low-passage expansion process to preserve cellular integrity and ensure maximum biological effectiveness.
Cryopreserved for Full Functionality
Exosomes are cryogenically frozen (never lyophilized), maintaining membrane integrity and peak signaling capacity.
Rigorous Testing & Traceability
Each batch is counted, characterized, and third-party tested for sterility, endotoxins, and mycoplasma, with full documentation provided.
Ethically Sourced & FDA-Compliant
Collected from full-term, healthy births in the U.S. under strict ethical and regulatory standards for quality and donor screening.
Multi-Targeted Application
Designed for topical use on skin, scalp, and hair, enhancing results post-microneedling, laser, or abrasion procedures with visible rejuvenation.
What are Exosomes?
Exosomes are small vesicles (30-150 nanometers in diameter) that are secreted by cells. They carry a variety of molecules, such as lipids, RNAs, hundreds of growth factors, cytokines and other functional proteins. They play an important role in cell-to-cell communication and signaling. Exosome treatments have recently emerged as a groundbreaking application in the field of aesthetics with unprecedented results for skin regeneration and hair re-growth.
Manufactured in the United States
Resiliélle’s AGE-ZERO™ exosomes harness the unparalleled power of Wharton’s Jelly Stem Cells, sourced from donated umbilical cords after healthy, full-term births. These cords are donated in strict compliance with FDA ethical standards. This unique source is believed to contribute to AGE-ZERO™ exosomes' exceptional potency, safety, and quality. We believe no other stem cell source offers the same promise for effectiveness and regenerative potential as these ethically sourced, "zero-aged" cells.Low Passage Manufacturing Process: Through a low passage expansion process, Resiliélle™ cultivates stem cells in a way that maintains their purity and quality. Exosomes are then harvested from the stem cell-conditioned media, ensuring they deliver optimal effectiveness with every application.
Quality: Resiliélle™ exosomes are carefully counted and characterized in their FDA Registered laboratories in New York. Each batch undergoes rigorous testing to ensure the highest standards of quality, consistency, and performance.
Safety: Safety is a top priority at Resiliélle™. Their donor screening includes a comprehensive infectious disease panel, and every final product is tested at an independent CLIA-certified lab for sterility, endotoxins, mycoplasma, and bioburden. A certificate of conformity accompanies each shipment, ensuring that their topical cosmetic exosome serum meets all safety and quality requirements.
Disclaimer: RESILIÉLLE™ exosomes are for topical cosmetic use only.
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Frozen, NEVER Lyophilized:
To maintain the exosomes’ integrity and maximize their effectiveness, Resiliélle™ never lyophilize (freeze-dry) their product. Lyophilization can damage the exosome membrane, which would limit its ability to deliver its vital molecular cargo. Their commitment to freezing ensures the exosomes remain fully functional.
“Off the shelf” exosomes suspended in sterile saline to maintain ultimate potency, never lyophilized.
What is the best source for exosomes?
Exosomes are released by virtually all types of living cells. But when looking for the ideal cell source for exosomes to be used in regeneration, we believe the cell of choice must be human stem cells. Stem cells are the ‘building blocks’ of life. They are characterized by the ability to self-renew and to differentiate into virtually every cell type. Exosomes derived from stem cells harness their potential for regeneration and repair. Among the various stem cell sources, perinatal stem cells are the most formidable ones, and exosomes derived from them are the most potent ones.
Yes. Exosomes themselves are natural components of the body, acting as messengers between cells. They are involved in various physiological processes and are generally not harmful. They have been shown to be effective and generally have not been found to cause any adverse effects. However, their source and quality are paramount. Resiliélle™ uses only ethically sourced umbilical cords from qualified donors in the US, and the MSC-derived Age-Zero Exosomes™ are ‘Made in USA’ as well, subject to extensive 3rd party pathogen testing, resulting in a best-in-class product.
Disclaimer: RESILIÉLLE™ exosomes are for topical cosmetic use only.
The FDA generally has no authority over products used in cosmetics or aesthetics. Thus, exosomes used for topical aesthetics applications are not subject to pre-market approval by the FDA. However, the MSCs used to derive Age Zero Exosomes™ are manufactured compliant with FDA standards.
Side effects or adverse events are rare, and typically minor, such as skin irritation or ‘flaking’. The latter is likely not caused by the exosomes but rather other products (gels or numbing creams) used in adjunct microneedling treatments that have not been properly removed. It is advised to discontinue use if irritation or a rash appears.
Yes. Your Exosome purchase includes top-tier training, delivered directly by the manufacturer’s experienced clinical team. The trainers are highly skilled professionals who ensure you and your staff feel confident, competent, and fully prepared to deliver safe and effective treatments from day one.
We’re here to help every step of the way!
Whether you're ready to get started or just have a few questions, we’d love to hear from you.
📞 Call or Text: (855) 342-7546
📧 Email: info@skinenergytech.com
No pressure, no hassle - just friendly support and honest answers. Let’s talk!